April 13-14, 2011
Washington DC
Walter Washington Convention Center
Room 152A/B
Chairs: John R. Hepler, Emory University, and Venetia
Zachariou, University of Crete, Greece
Wednesday, April 13
1:30 pm Registrant
Check-in
2:00 pm Welcome
and Overview
J.
R. Hepler and V. Zachariou
RGS/AGS Proteins
in Physiology and Disease
A) Visual System
Chair: Kirill Martemyanov, Univ. of MInnesota
2:15 pm R7 RGS Regulation of Class A and Class C GPCR Pathways
Ted
Wensel, Baylor College of Medicine
2:45 pm AGS/PcP2/Go Signaling in Retina
Noga
Vardi, Univ of Pennsylvania
3:15 pm Break
B) Inflammation and
Cardiovascular disease
Chair: Kendall Blumer, Washington Univ
3:30 pm RGS in Bronchial Smooth Muscle/Asthma
Kirk Druey, NIAID/NIH
4:00 pm RGS Modulation of Myocyte Stress Responses in Heart Disease
David Kass, Johns Hopkins Univ
4:30 pm RGS Proteins in Cardiovascular Function
Scott Heximer, Univ of Toronto
5:00 pm Registrant
Check-in
Break for Posters and Dinner
Note:
Anyone registered for the EB2011 meeting may attend this first
session. To attend the posters, dinner,
evening and Thursday sessions, you must register SEPARATELY for this
colloquium.
C) Cancer and
Neoplastic Disease
Chair: Thomas Wilkie, Univ of Texas Southwestern Medical Ctr at Dallas
6:30 pm RGS Proteins in Ovarian Cancer
Shelley
Hooks, Univ of Georgia
7:00 pm AGS Proteins and Cancer Biology
Stephen Lanier, Medical Univ of South Carolina
7:30 pm AGS Protein PINS in Asymmetric Cell Division
Christopher Johnston, Univ of Oregon
8:00 pm RGS Genes - HTS Biomarkers for Pancreas Development, Cancer and Diabetes
Ozhan Ocal, Univ of Texas Southwestern Medical Ctr at Dallas
D) CNS Disorders
Chair: Venetia Zachariou, Univ of Crete, Greece
8:15 PM RGS4 in Bipolar Disorders/Schizophrenia
Ashok
Hegde, Wake Forest Univ.
8:45 pm RGS10 in Microglia and CNS Inflammation
Malu
Tansey, Emory Univ.
9:15 pm Roles of Membrane Anchoring Subunits in Determining Expression, Subcellular Targeting and Activity Regulation of RGS9/Gß5 GAP Complex in photoreceptor Neurons
Yan Cao, Univ of Minnesota
Thursday, April 14, 2011
7:00 am
Continental Breakfast (and poster viewing)
RGS and AGS
Proteins and Their Partners as Drug Targets
E) The RGS/AGS/G
Protein Interface as Drug Targets
Chair: Alan Smrcka, Univ of Rochester Sch of Medicine & Dentistry
8:00 am RGS
Proteins as Drug Targets
Richard
Neubig, Univ of Michigan
8:30 am Structure/Function of RGS & AGS Proteins
David Siderovski, Univ of North Carolina-Chapel Hill
9:00 am AGS3 and GIV Regulate Authophagy by Balancing G Protein Activity and Growth Factor Signals
Mikel Garcia-Marcos, Univ of California, San Diego
F) Genetic Systems and Structure/Function
Chair: Henrik Dohlman, Univ of North Carolina
9:15 am AGS-3 regulates Gαo signaling in C. elegans to allow behavioral responses of to food deprivation
Michael
Koelle, Yale Univ
9:45 am Structural analysis of RGS Protein Interactions
John Tesmer, Univ of Michigan
10:15 am Pressure Overload Hypertrophy in Transgenic Mice with Cardiac-specific RGS2 Expression
Cindy Park, Brown Univ
10:30 am Break
G) RGS/AGS Binding
Partners and Signaling Complexes
Chair: Peter Chidiac, Univ of Western Ontario
10:45 am Ric8A Regulation of AGS/G Protein Complexes
Gregory G.
Tall, Univ of Rochester
11:15 am Coupling of RGS and AGS Proteins with GPCRs
Joe Blumer, Medical Univ of Southe Carolina
11:45 am When the G Protein is an AGS Protein: Mechanistic Insights of Signal Initiation from a Crystal Structure of a Self-activating G-alpha Subunit
Janice Jones, Univ of North Carolina
12:00 noon - Adjournment
REGISTRATION:
Early Registration Until Midnight, March 31, 2011.
ASPET Members - $200.00 (Login to register at the member reduced rate)
Non-ASPET Members - $325.00
Students/Fellows - $75.00
Non-ASPET Members - Register here.