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3rd GPCR Colloquium

April 27-28, 2007
Washington Convention Center Room 204A-C

Washington, DC

Chairs:  Kim A. Neve and Olivier Civelli

ASPET gratefully acknowledges the educational grants from AstraZeneca, Johnson & Johnson, Merck Research, Wyeth Research, and the ASPET Division for Neuropharmacology, with support for the Keynote Lecture on day 2 by the ASPET Division for Molecular Pharmacology


 

Friday, April 27
8:10 AM - 5:00 PM



 

7:30 am            Continental breakfast

 
8:10 am             The structural basis for GPCR oligomerization: Implications for activation
                              Jonathan A. Javitch, Columbia University College of Physicians and Surgeons
 

8:50 am            Heterooligomerization of Class A GPCRs creates novel signaling units distinct from their
                        constituent GPCR homooligomers

                              Susan R. George, University of Toronto

 

9:30 am             GPCR ligand binding and release: Insights and mysteries
                               David L. Farrens, Oregon Health and Science University

 

10:10 am           Coffee & posters in room 206

 

10:40 am           G proteins and their accessory proteins
                              Stephen M. Lanier,
Medical University of South Carolina
 

11:20 am           Is Helix VIII of G Protein-Coupled Receptors (GPCRs) a lipid-activated signalling
                         sensor?

 
                             John Huynh, Baker Heart Research Institute, Australia

 

11:50 am           Lunch

 

1:20 pm            Interactions between GPCRs and receptor tyrosine kinases
                             
Kevin J. Catt
, NICHD, NIH


2:00 pm            GPCRs, arrestins, and ubiquitination
                             
Sudha K. Shenoy, Duke University Medical Center

  

2:40 pm            Allosteric agonists and allosteric modulators are differentially affected by mutations 
                       
within the allosteric binding pocket of M2 muscarinic acetylcholine receptors.     

                              Karen Gregory, Monash University, Australia

 

3:10 pm           Coffee & posters in room 206

 

3:40 pm            Multiplexing resonance energy transfer approaches to study GPCR signaling complexes inliving cells
    
Michel Bouvier,
University of Montreal

 

4:20 pm            Use of genetically engineered mice to unravel the functions of dopamine receptors
                             
Emiliana Borrelli
, University of California, Irvine

 

5:00 pm            Wine & cheese reception/poster presentation in room 206
 

 

 

 

 

 

Saturday, April 28 
8:20 AM - 4:30 PM

 


 

7:30am             Continental breakfast

 

8:20am             Kisspeptin and GPR54 in the regulation of puberty and reproduction
                             
Ursula Kaiser, Brigham & Womens Hospital, Harvard Medical School

 

9:00 am            GPCRs in arousal and anxiety
                             
Rainer K. Reinscheid, University of California, Irvine

 

9:40 am            Vasoactive intestinal polypeptide receptor 2 female knockout mice are resistant to diet-
                        induced obesity
                            
 Mari Candelore, Merck & Company

 

9:55 am            Dynorphin A activates bradykinin receptors to maintain neuropathic pain
                             
Josephine Lai, University of Arizona Health Sciences Center                       

 

10:10 am           Coffee break

 

10:40 am           The role of GPR30 in estrogen signaling
                             
Eric R. Prossnitz, University of New Mexico Health Sciences Center
 

11:20 am          Inverse agonist vs. full antagonist properties of rimonabant in systems with
                       overexpressed vs. native CB1 receptors 
                            
Douglas Greene, Sanofi-aventis

 

12:00 noon        Lunch

 

1:30 pm            Novel aspects of the melanocortin receptors
                             
Roger D. Cone, Oregon Health and Science University

 

2:10 pm            Leucocyte chemoattractant receptors: New molecules and new concepts
                             
Marc Parmentier, Free University of Brussels

 

2:50 pm            Break

 

3:20 pm                                                  Special Lecture                                                             
The function and regulation of G protein coupled glutamate receptors in the 
neural network
Shigetada Nakanishi, Osaka Bioscience Institute
 

4:30 pm             End of Meeting

Continental Breakfast and lunch will be provided both days.
Pre-registration deadline is April 6, 2007.

Registration Form
You may register online by filling in form and clicking the SUBMIT button
or
Complete form online, print and mail to Margie Arkin, ASPET, 9650 Rockville Pike, Bethesda, MD  20814.

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