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ACE2/Angiotensin-(1-7)/Mas Receptor Axis: Look, How Far We've Come!

Sunday April 07, 2019

8:00 am - 10:00 am

Room W206 A
Co-sponsored by the Division for Cardiovascular Pharmacology (CVP)
Co-sponsored by the Division for Drug Discovery and Development (DDD)
Co-sponsored by the Division for Molecular Pharmacology (MP)

Chair :

Yagna Jarajapu
North Dakota State University

Rita Valentino
National Institute on Drug Abuse


The alternative axis of renin angiotensin system, ACE2/Angiotensin-(1-7)/Mas receptor, has attracted massive interest among academia and industry. Originally seen as counterbalancing the ACE/Ang II axis in cardiovascular system, increased understanding of the biologic effects of Angiotensin-(1-7) has shown that this pathway is relevant for diseases of other organ systems including hematologic, neurologic, vascular, musculoskeletal and metabolic disorders. Advancements range from it’s interaction with gut-microbiome and non-addictive analgesia to stimulation of endothelial cells and their progenitors for the treatment of ischemic disorders. This symposium will update the ASPET community with the recent advancements and discuss novel hypotheses and pharmacotherapeutic opportunities.

Neuropharmacology of Angiotensin-(1-7)/Mas Receptor Pathway
Robson Santos - Federal University of Minas Gerais

ACE2 and Sex-Differences in Obesity-Induced Hypertension
Robin Shoemaker - University of Kentucky

ACE2 in the Gut-Brain Axis in Cardiopulmonary Diseases
Mohan Raizada - University of Florida College of Medicine

Angiotensin-(1-7)/Mas Receptor Pathway: A Novel Non-Addictive Analgesic Target
Todd Vanderah - University of Arizona

Angiotensin-(1-7): Mechanism to Medicine
Richard Franklin - Constant Pharmaceuticals

Last Updated: August 15, 2019
Key Dates
April 6

ASPET Business Meeting and Awards Presentation

April 6-9

ASPET Annual Meeting at EB 2019

Thank you to our Annual Meeting partners:

Amgen
University of Florida
Wake Forest University
Washington State University College of Pharmacy and Pharmaceutical Sciences
University of Wisconsin Molecular and Cellular Pharmacology Training Program
UT Health San Antonio
University of Minnesota

Emory University Pharmacology

PR & P
University of Michigan Medical School Pharmacology
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