In This Section

News Detail

Molecular Pharmacology Highlighted Trainee Author, November 2019

October 16, 2019

Doyoung KwonDoyoung Kwon is the Molecular Pharmacology Highlighted Trainee Author for the November 2019 issue.  Dr. Kwon is a postdoctoral trainee at the University of California at San Francisco.  His mentor is Professor Maria Almira Correia. The Molecular Pharmacology article that earned his selection as a Highlighted Trainee Author is titled “Induction via Functional Protein Stabilization of Hepatic Cytochromes P450 upon gp78/Autocrine Motility Factor Receptor (AMFR) Ubiquitin E3-ligase Genetic Ablation in Mice: Therapeutic and Toxicological Relevance” and is available at http://molpharm.aspetjournals.org/content/96/5/641.

Dr. Kwon’s areas of research are pharmacology and toxicology associated with hepatic cytochrome P450 enzymes (P450s). P450s are a major hepatic phase I drug-metabolizing enzymes that biotransform diverse xenobiotics and endobiotics, including drugs, chemicals, fatty acids, and hormones, and play an important role in the pathogenesis of liver disease. Specifically, Dr. Kwon studies the mechanisms of hepatic P450 protein degradation and assesses their pharmacological and toxicological relevance using in vitro and in vivo model systems.

The anticipated impact of Dr. Kwon’s research is the understanding of P450 regulation, especially via its protein degradation, to determine the clinical implications for hepatic drug metabolism and drug-drug interactions.

When not in the lab, Dr. Kwon enjoys playing soccer and is a big fan of the football club Barcelona. These days, making eye contact with his baby princess, Olivia, is the greatest joy of his life.

Related Files:
Categories:
  • Journal News
Last Updated: September 18, 2019

Job Postings