Sunday, May 19
Focus: Making a Better Molecule
3:00 pm – 3:10 pm | Welcome
3:10 pm – 3:50 pm | Building Better p97 / VCP Inhibitors to Treat Cancer
Keynote: Donna Huryn, PhD, University of Pennsylvania
3:50 pm – 5:10 pm | Sessions
3:50 pm – 4:10 pm
Bill Messer, Univ of Toledo
Allosteric modulation of Neurotransmitter Efficacy in Drug Development for Neurological Disorders
4:10 pm – 4:30 pm
Jay Wright, Univ of Michigan
Expanding Radiochemical Space with New Radiolabeling Reactions
4:30 pm – 4:50 pm
Corey Hopkins, University of Nebraska Med Ctr and Sumaiya Nahid, University of Nebraska
Discovery of GIRK ½ Activators as Non-opioid Analgesics
4:50 pm – 5:10 pm
Aleksey Gerasyuto, Schroedinger Therapeutics Group
The Predict-First Paradigm: How Digital Chemistry is Shaping the Future of Drug Discovery
5:15 pm – 7:15 pm | Poster Presentation & Reception
Monday, May 20
Focus: Understanding Drug Action
8:30 am – 8:35 am | Introduction
8:35 am – 9:15 am | Keynote: Richard R. Neubig, MD, PhD, Michigan State University
From the Membrane to the Nucleus, A Drug Discovery Journey
9:15 am – 9:55 am | Sessions
9:15 am - 9:25 am
Shubhra Saha, NIH
Activation of PTH1 Receptor using Chimeric Peptide Templated in situ Click Reaction of Nanobody Conjugates
9:25 am – 9:35 am
Kir Synder, NIH
Discovery, Characterization, and Optimization of a Novel Positive Allosteric Modulator-Antagonist of the D3 Dopamine Receptor
9:35 am – 9:55 am
Wei Wang, Univ Arizona
Control Activities of PROTACs by Bioorthogonal Chemistry
Mengyang Chang, Univ Arizona
Bioorthogonal PROTAC Prodrugs Enabled by On-Target Activation
9:55 am – 10:15 am | Sponsor Highlight
Peter Gedeck, CDD
Accelerating Research and Collaboration with CDD Vault: Your Unified Platform for Scientific Truth
10:15 am – 10:55 am | Sponsor Networking Break
Focus: Transitioning from Academia to Biotech
10:55 am – 11:00 am | Introduction
11:00 am – 12:20 pm | Sessions
11:00 am – 11:20 am
Harshini Neelakantan, Ridgeline Therapeutics
Insights from an Uncovered Path to Biotech from Academia
11:20 am – 11:40 am
Nick Cosford, Sanford Burnham/Camino and Patrick Hagan, Sanford Burnham/Camino
11:40 am – 12:00 pm
Andrew J. Storaska, Rothwell Figg
Navigating the IP Space as an Academic Researcher
12:00 pm – 12:20 pm
Matthias Buetikofer, ETH Zurich
Ultrafast Fragment Screening and Affinity Determination using Photo-Boosted NMR
12:20 pm – 1:50 pm | Lunch and Sponsor Networking
Focus: Disease Biology informs Therapeutic Discovery
1:50 pm – 1:55 pm | Introduction
1:55 pm – 3:15 pm | Sessions
1:55 pm – 2:15 pm
Godwin Dziwornu, Univ. of Cape Town
The Antibiotic Fusidic Acid Targets Elongation Factor G in Mycobacterium Tuberculosis
2:15 pm – 2:35 pm
Charisse Winston, Keck School of Medicine of USC
Extracellular Vesicles as Biomarkers for Alzheimer's Disease and Other Age-Related Dementias
2:35 pm – 2:55 pm
Shajila Siricilla, VUMC
Identification of Therapeutics for Management of Preterm Birth
2:55 pm – 3:05 pm
Alexis Surtel, NIH
Neuroprotection in C. Elegans Parkinson's Disease Models: Discovering Therapeutic Insights via RNAi and Small Molecule High Throughput Screening
3:05 pm – 3:15 pm
Maaike Everts, Critical Path Institute
C-Path's Translational Therapeutics Accelerator: A Unique Solution to Successfully Bridge the Valley of Death in Academic Drug Discovery and Development
3:15 pm – 3:35 pm | Sponsor Networking Break
Focus: The Start Defines the Project
3:35 pm – 3:40 pm | Introduction
3:40 pm – 4:45 pm | Sessions
3:40 pm – 4:00 pm
Barbara Slusher, JHMI and Diane Peters, JHMI
Development of a Gut-Restricted GCPII Inhibitor for Inflammatory Bowel Disease
4:00 pm – 4:40 pm | Keynote: Michelle Arkin, PhD, University of California, San Francisco
Linking Chemical Fragments and Connecting Across Cultures
4:40 pm – 4:45 pm | Closing Remarks