This session will feature a talk from the Okita Early Career Award recipient, followed by two talks from the authors of the best papers of 2022 from the journal of Drug Metabolism and Disposition who received the James R. Gillette Awards in pharmacokinetics/transporters and drug metabolizing enzymes. The session will also include abstract-based oral presentations from graduate students and postdoctoral fellows focused on drug metabolism and disposition.The Richard Okita Early Career Award has been established by the ASPET Division for Drug Metabolism and Disposition to recognize excellent original research by early career investigators in the area of drug metabolism and disposition.