Program

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Muscarinic Receptors in Stages of Alcohol and Substance Use Disorders

Sunday May 21, 2023

9:00 am - 10:30 am Central Time (CT)





Chair :

Morgane Thomsen
Region Hovedstadens Psykiatri and University of Copenhagen

Leigh Walker
Florey Institute of Neuroscience and Mental Health



This session compare and contrast the impact of selective modulation of muscarinic receptor subtypes across the addiction cycle of different addictive substances. Dr. Thomsen will discuss effects of M1 and M4 mAChR ligands on aspects of cocaine self-administration including choice, and cognitive disturbances. Dr. Banks's findings will highlight how M1 mAChR effects on methamphetamine vs food choice compare to those cocaine effects. Ms. Teal will contrast the effect of M1 and M5 mAChR ligands on aspects of opioid drug taking and seeking. Dr. Walker will present M4 and M5 mAChR ligand effects on alcohol taking and seeking in different brain regions in rats and humans.

Speakers

Morgane Thomsen - Region Hovedstadens Psykiatri and University of Copenhagen

Leigh Walker - Florey Institute of Neuroscience and Mental Health

Introduction

Morgane Thomsen - Region Hovedstadens Psykiatri and University of Copenhagen

Acute and Long-term Effects of M1/M4 Reception Stimulation on Aspects of Cocaine use Disorder

Matthew Banks - Virginia Commonwealth University

Effects of M1 Receptor Activation on Methamphetamine-vs-Food

Laura Teal - Vanderbilt University

M5 Receptor Modulation Across Stages of Opioid use Disorder

Leigh Walker - Florey Institute of Neuroscience and Mental Health

M4 and M5 Muscarinic Receptors Regulate Different Aspects of Alcohol Consumption and Seeking

Morgane Thomsen - Region Hovedstadens Psykiatri and University of Copenhagen

Discussion and Conclusion

ASPET 2023 Annual Meeting Program
Important Dates

Apr

20

Registration Discounts End

Apr

14-24

Division Town Halls

Apr

24

Housing Deadline

May

3-10

Online Award Lecture Series

May

18-21

ASPET 2023 Annual Meeting
St. Louis Union Station, MO