G protein-coupled receptor (GPCR) signal transduction is involved in virtually all aspects of human physiology, and its dysregulation gives rise to many neurological, metabolic, and cardiovascular diseases as well as cancer. Accordingly, GPCRs are the targets of ~33% of clinically used medications. This ASPET colloquium will highlight recent breakthroughs in understanding GPCR signaling mechanisms and their implications for human health and drug development.
Join us for this all-day satellite event on Wednesday, May 20 at the Hyatt Regency Minneapolis, held in conjunction with the ASPET 2026 Annual Meeting. Extra-fees apply.
Note: The morning program runs concurrently with the ASPET Annual Meeting.
9:15 am – 9:30 am
Welcome and Introductory Remarks by the Organizing Committee
9:30 am - 10:15 am
Keynote: Jeff Benovic Thomas Jefferson University, Professor Topic: Past, Present, and Future of GRK and Arrestin Regulation of GPCR Signaling
10:15 am – 10:45 am
Coffee Break / Networking
10:45 am – 12:15 pm
Session 1: Molecular, Cellular, and Spatial Dynamics of GPCR Signaling
10:45 am – 11:05 am Vselvolod (Seva) Gurevich Vanderbilt University, Professor Topic: GPCR-independent functions of b-arrestins and the role of arrestin dynamics
11:05 am – 11:25 am Makaia Papasergi-Scott University of Rochester, Assistant Professor Topic: Time-resolved cryo-EM of G protein activation
11:25 am – 11:45 pm Alan Smrcka University of Michigan, Professor Topic: G protein/PLC signaling nanodomains in heart failure
11:45 pm – 12:05 pm Roshanak Irannejad University of California San Francisco, Associate Professor Topic: Monoamine transporters and intracellular GPCR signaling
12:05 pm – 12:15 pm A trainee speaker will be selected from submitted abstracts
12:15 pm – 12:30 pm
Networking in the Colloquium room with speakers/ attendees prior to lunch
12:30 pm – 2:30 pm
COLLOQUIUM PAUSES. GUESTS ATTEND ANNUAL MEETING AWARD LUNCH
2:30 pm – 4:00 pm
Session 2: Structure-Based Drug Discovery
2:30 pm – 2:50 pm JoAnn Trejo University of California San Diego, Professor Topic: Arrestins and a-arrestins in cancer progression and inflammation
2:50 pm – 3:10 pm Adriano Marchese Medical College of Wisconsin, Professor Topic: Arrestin-dependent and independent GPCR trafficking and signaling
3:10 pm – 3:30 pm John Tesmer Purdue University, Professor Topic: Structure based GRK drug discovery
3:30 pm – 3:50 pm Nina Tsvetanova Duke University, Assistant Professor Topic: GPCR signaling from endomembranes
3:50 pm – 4:00 pm A trainee speaker will be selected from submitted abstracts
4:00 pm – 4:45 pm
Keynote: Mark Von Zastrow University of California San Francisco, Professor Topic: Functional specialization of GPCR signaling by β-arrestins
4:45 pm – 6:30 pm
Poster Session – Networking - Mixer
6:30 pm
Colloquium adjourns (dinner on own)
Abstract submission deadline: December 4, 2025 Poster presenters for the colloquium will be selected from abstracts submitted by December 4 to ASPET Annual Meeting specifically within the GPCR topic category (#3.6-GPCR). Accepted posters will be presented at both the colloquium on Wednesday, May 20 and scheduled to present during one of the main ASPET Annual Meeting poster sessions on Sunday-Tuesday, May 17-19.
This is a satellite meeting to ASPET Annual Meeting. The colloquium ticket fee will be in addition to your Annual Meeting registration fees. Registration is expected to open in late October.
Contact ASPET Meetings with questions.
Interested in partnering with us? Learn More. Contact us at partnerwithus@aspet.org.
Sep
4
Session Proposals Due
Dec
Travel Award and Poster Competition Applications Due
Travel Award Applications Due
Feb
10
Deepest Registration Discounts End
Mar
Division Town Halls
Apr
21
Registration Discounts End
May
17-20
ASPET 2026 Annual Meeting
20
GPCR Colloquium
Jun
Online Award Lectures