The Axelrod Symposium honors the memory and pioneer work by Dr. Julius Axelrod who made fundamental discoveries on the synthesis, signaling and neuroendocrine actions of melatonin, a molecule that signals darkness.  The distinguished panel of speakers will address the molecular and neuropharmacological mechanisms of melatonin receptor function, and the potential of novel melatonin receptor ligands to treat circadian disorders, depression, cancer, and type 2 diabetes  among other conditions and diseases.