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Division for Drug Metabolism and Disposition James R. Gillette Award

Award Description | Presentation | Nomination Criteria and ProcessPrior Recipients 

Award Description 

The James R. Gillette Award is presented each year for two outstanding papers published in Drug Metabolism and Disposition, one each in the broad categories of a) Drug Metabolism and b) Disposition and Pharmacokinetics.

Presentation

The award is presented annually. The award consists of:

  • Invitation to the first author to present the work at a platform session at the annual meeting
  • Travel support and complimentary registration at the annual meeting
  • Cash award of $250 for the first author

Nomination Criteria and Process

All manuscripts published in Drug Metabolism and Disposition (DMD) in a given calendar year are eligible. After the last issue of the year has closed, the DMD editor provides a list of the nominated manuscripts to the Drug Metabolism Division.

Selections are made based on the primary review of the manuscript for publication, followed by a secondary review by the James R. Gillette Best Paper Award Committee. The Award Committee consists of members of the executive committee, is chaired by the Division for Drug Metabolism’s Past-Chair, and may include outside expertise as necessary. Award winners are selected at the end of the calendar year, and notified in January or February.

Award Recipients

2015

Drug Metabolism category: Yun-Chen Tien accepted the award “Dose of Phenobarbital and Age of Treatment at Early Life are Two Key Factors for the Persistent Induction of Cytochrome P450 Enzymes in Adult Mouse Liver.” Drug Metabolism Disposition, December 2015, 43:1938-1945. Dr. Tien’s paper was presented by Xiaobo Zhong. 

Pharmacokinetics/Drug Transporters category: Li Liu accepted the award “Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study.” Drug Metabolism Disposition, November 2015, 43:1795-1804. Dr. Liu’s paper was presented by Jashvant Unadkat.

2014

Drug Metabolism category: Kunzhi Jia accepted the award “Generation and Characterization of a Novel CYP2A13-Transgenic Mouse Model.” Drug Metabolism Disposition, August 2014, 42:1341-1348. Dr. Jia’s paper was presented by Xinxin Ding. 

Pharmacokinetics/Drug Transporters category: Toru Takenaka accepted the award “Human Small Intestinal Epithelial Cells Differentiated from Adult Intestinal Stem Cells as a Novel System for Predicting Oral Drug Absorption in Humans.” Drug Metabolism Disposition, November 2014, 42:1947-1954.

2013

Drug Metabolism category: Amarjit S. Chaudhry accepted the award “Genetic variation in aldo-keto reductase 1D1 (AKR1D1) affects the expression and activity of multiple cytochrome P450s.” Drug Metabolism Disposition, August 2013, 41:1538-1547. 

Pharmacokinetics/Drug Transporters category: Toshiyuki Kudo accepted the award “Analysis of the repaglinide concentration increase produced by gemfibrozil and itraconazole based on the inhibition of the hepatic update transporter and metabolic enzymes.” Drug Metabolism Disposition, February 2013, 41:362-371.

2012

Drug Metabolism category: Manabu Matsunawa “Vitamin D Receptor Activation Enhances Benzo[a]pyrene Metabolism via CYP1A1 Expression in Macrophages.” Drug Metabolism Disposition, November 2012, 40:2059-2066. Dr. Matsunawa’s paper was presented by Shigeyuki Uno.

Pharmacokinetics/Drug Transporters category: Hamsell M. Alvarez accepted the award “Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice.” Drug Metabolism Disposition, February 2012, 40:360-373. 

2011

Drug Metabolism category: Kyoung Noh accepted the award “Farnesoid X Receptor Activation by Chenodeoxycholic Acid Induces Detoxifying Enzymes through AMP-Activated Protein Kinase and Extracellular Signal-Regulated Kinase 1/2-Mediated Phosphorylation of CCAAT/Enhancer Binding Protein β.” Drug Metabolism Disposition, August 2011, 39:1451-1459.

Pharmacokinetics/Drug Transporters category: Xuena Lin accepted the award “Attenuation of Intestinal Absorption by Major Efflux Transporters: Quantitative Tools and Strategies Using a Caco-2 Model.” Drug Metabolism Disposition, February 2011, 39:265-274. 

2010

Drug Metabolism category: Fang Li accepted the award “Ecto-5'-Nucleotidase and Thiopurine Cellular Circulation: Association with Cytotoxicity.” Drug Metabolism Disposition, December 2010, 38:2329-2338. 

Pharmacokinetics/Drug Transporters category: Tomoya Yasujima accepted the award “Evaluation of 4',6-Diamidino-2-phenylindole as a Fluorescent Probe Substrate for Rapid Assays of the Functionality of Human Multidrug and Toxin Extrusion Proteins.” Drug Metabolism Disposition, April 2010, 38:715-721.

2009

Drug Metabolism category: Natasha DeVore accepted the award “Key residues controlling binding of diverse ligands to human cytochrome P450 2A enzymes.” Drug Metabolism Disposition, June 2009, 37:1319-1327.

Pharmacokinetics/Drug Transporters category: Katharine Howe accepted the award “In Silico and in Vitro Modeling of Hepatocyte Drug Transport Processes: Importance of ABCC2 Expression Levels in the Disposition of Carboxydichlorofluroscein.” Drug Metabolism Disposition, February 2009, 37:391-399.


Last updated: November 11, 2016 

Last Updated: August 23, 2017

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