Focus on Pharmacology: Operational Models in Pharmacology

Hosted by the ASPET Division for Molecular Pharmacology (MP)

Wednesday, December 7, 2022, 4:00 pm – 5:00 pm ET

This interactive webinar will teach participants how to apply operational models to quantify agonism or allosterism, commonly applied analytical frameworks for GPCR pharmacology. Critical elements of experimental design and core assumptions will be discussed, as well as how these methods can enrich drug discovery.

Moderator

Francesco De Pascali, PhD – Thomas Jefferson University

Speaker

Karen Gregory, PhD – Monash University

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on ASPETConnect

Focus on Pharmacology: Current Advances in Drug Metabolism Part 5

Hosted by the ASPET Division for Drug Metabolism and Disposition (DMDD)

Monday, December 12, 2022, 2:30 pm – 3:30 pm ET

The DMDD Quarterly Webinar Series is intended to stimulate idea exchange and communication among DMDD members and to promote career development of young scientists in the field of drug metabolism and disposition.

Join us for this session where our featured junior scientists will discuss recent advancements in pharmacokinetic interactions between natural products and drugs as well as the functional consequences of HO-1: CYP1 complex formation. 

Speakers

John Clarke, PhD, Washington State University
Simple versus complex mechanisms for pharmacokinetic natural product-drug interactions

John P. Connick, PhD, Louisiana State University Health Sciences Center
Characterization of the functional consequences of HO-1: CYP1 complex formation

Organizers

Hyunyoung Jeong, PhD, Purdue University

Julie Lade, PhD, Amgen

With special thanks to our additional moderators and Q&A facilitators: Haojie Zhu, Julie Lade, Joanne Wang and Colten Eberhard.



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on ASPETConnect

Focus on Pharmacology: High-Content Imaging for Analysis of Signal Transduction in Heterogeneous Cell Populations

Hosted by the ASPET Division for Molecular Pharmacology (MP)

Wednesday, October 12, 2022, 12:00 pm – 1:00 pm ET

This webinar will provide trainees and interested researchers with the background and practical insights into understanding and using high-content imaging for cellular studies. In particular, the workshop will focus on how to use this technique as it relates to cluster analysis of single-cell type responses in a mixed population, how it can be applied to the fields of molecular pharmacology and cell signaling, and what is needed to perform high-content imaging.

Moderator

Khairunnisa Semesta - Duke University

Speakers

Carmen Dessauer, PhD - McGovern Medical School

Anibal Garza Carbajal, PhD - McGovern Medical School

View Session Recording
on ASPETConnect

Focus on Pharmacology: Current Advances in Drug Metabolism Part 4

Hosted by the ASPET Division for Drug Metabolism and Disposition (DMDD)

Friday, September 30, 2022, 2:00 pm – 3:00 pm ET

The DMDD Quarterly Webinar Series is intended to stimulate idea exchange and communication among DMDD members and to promote career development of young scientists in the field of drug metabolism and disposition.

Join us for this session where our featured junior scientists will discuss recent advancements in interindividual variability in drug metabolism and bioactivation and CYP4 enzymes at the interface of xenobiotic and endobiotic metabolism.  

Moderator

Joanne Wang, PhD - University of Washington

Speakers

Klarissa Jackson, PhD - University of North Carolina at Chapel Hill
Interindividual Variability in Drug Metabolism and Bioactivation in Ethnically Diverse Populations

Ryan Seguin, PhD- University of Washington
Metabolic Fate of Benzalkonium Chlorides and Interactions with CYP4 Enzymes

With special thanks to our additional moderators and Q&A facilitators: Haojie Zhu, Hyunyoung Jeong, Julie Lade, and Colten Eberhard.

View Session Recording
on ASPETConnect

Focus on Pharmacology: RNAscope: RNA in Situ Hybridization Made (Relatively) Easy

Hosted by the ASPET Division for Molecular Pharmacology (MP)

Wednesday, August 10, 2022, 12:00 pm – 1:00 pm ET

This session will be about RNA in Situ Hybridization – a powerful alternative to immunohistochemistry. It allows you to determine which genes are expressed in specific cells or tissue. It is particularly useful when good antibodies for your protein are not available. The technique itself is not very new, but RNA in situ hybridization used to be very tricky to perform. Because of that many people stay away from it. RNAscope changed that and made RNA in Situ Hybridization accessible to many labs. Many researchers wanting to know the spatial expression of specific genes will benefit from this session. Pros and cons of this technique will be discussed, and members of the audience can ask the questions at the end.

Moderator

Isaac Fisher, PhD, Purdue University

Speaker

Alexey Pronin, PhD, Aromyx Corporation
RNAscope: RNA in Situ Hybridization Made (Relatively) Easy

View Session Recording
on ASPETConnect