Xinwen Wang is the Drug Metabolism and Disposition Highlighted Trainee Author for the January 2020 issue. Dr. Wang is a postdoctoral fellow at the University of Michigan, Ann Arbor. Her mentor is Dr. Haojie Zhu. The Drug Metabolism and Disposition article that earned her selection as a Highlighted Trainee Author is titled “Comparative Proteomics Analysis of Human Liver Microsomes and S9 Fractions” and is available at https://doi.org/10.1124/dmd.119.089235
Dr. Wang’s areas of research are pharmacokinetics, pharmacogenomics, proteomics, and metabolomics in the context of precision medicine. Her current research focuses on identifying genetic and non-genetic factors that contribute to interindividual variability in drug metabolism and disposition using multiple omics (e.g., pharmacogenomics, proteomics, and metabolomics) in both basic and clinical settings. Dr. Wang is working to improve our understanding of the variations of drug-metabolizing enzymes and transporters, and the associated interindividual variability in the disposition and therapeutic efficacy of various medications.
The anticipated impact of Dr. Wang’s current research is expected to improve the therapeutic outcomes of numerous drugs by identifying biomarkers that can predict individual drug responses and applying these biomarkers to precision pharmacotherapy.
When not working, Xinwen enjoys cooking, running with her dog, and playing with her daughter.