In This Section

Humanized in vitro and in vivo Models in Drug Discovery and Development

Sunday April 22, 2018

9:30 am - 12:00 pm Eastern Time (ET)

Room 15B


Chair :

Aarti Sawant-Basak
Pfizer Inc.

Xinxin Ding
University of Arizona

Increasingly sophisticated, powerful in vitro and in vivo models are being developed for drug discovery and development, which are complex to understand or master for the average users. Thus, the objective of this symposium is to bring experts on the generation and utility of such in vitro and in vivo models together to present the latest developments, discuss potential pitfalls and challenges, and showcase successful applications of the models in drug discovery and development research, driving appreciation for novel approaches and perhaps new collaborations.


Shyam Sundhar Bale - Draper Laboratories

Capturing Liver Function In Vitro: Micro-engineered Biomimetic Liver Platforms for Drug Metabolism and Inter-organ Interactions

Murat Cirit - MIT – Translational Center of Tissue Chip Technologies

Quantitative DMPK Applications of Microphysiological Systems

Karl-Dimiter Bissig - Baylor College of Medicine

Human Liver Chimeric Mice to Predict Human Drug Metabolism and Toxicity: The Chances and Challenges

Shujuan Chen - University of California, San Diego

Glucuronidation in Humanized and Conditional Knockout Animal Models

Piyush Bajaj - Takeda Pharmaceuticals

Industrial Perspectives of Microphysiological Systems in Drug Discovery and Development