Salwa Aburageh Said Abuiessa is the Journal of Pharmacology and Experimental Therapeutics Highlighted Trainee Author for the May 2020 issue.  Ms. Abuiessa is a pre-doctoral trainee at the Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria University in Egypt. Her mentor is Dr. Mahmoud El-Mas.  The Journal of Pharmacology and Experimental Therapeutics article that earned her selection as a Highlighted Trainee Author is titled “Pre-eclamptic Fetal Programming Alters Neuroinflammatory and Cardiovascular Consequences of Endotoxemia in  Sex-Specific Manners” and is available at https://doi.org/10.1124/jpet.119.264192.

Ms. Abuiessa’s area of research is cardiovascular pharmacology. She looks at how preeclampsia would program maternal and fetal cardiovascular health and responsiveness to stressors like sepsis.  In addition, she studies how preeclamptic programming would affect the inflammatory and hemodynamic consequences of endotoxemia in both mothers and adult rat offspring and if there is sex specificity in this programming profile.  Specifically, her focus is on the possible role played by the renin angiotensin system in the pathogenesis of the preeclamptic disorder. 

The anticipated impact of Ms. Abuiessa’s research is through the examination of the potential role of a disrupted renin angiotensin system in the pathogenesis of preeclampsia.  Her research is likely to impact and improve: 1) the understanding of the pathogenesis of preeclampsia, 2) the identification of new joint targets for more holistic disease treatment options, 3) exploring sex-related vulnerability to preeclamptic programming of cardiovascular health of adult offspring, and 4) advancing awareness of the developmental origins of cardiovascular disorders.

When not in the lab, Ms. Abuiessa enjoys cooking and shopping and playing with her beloved daughters, Lilian and Mirna.