Victoria Oyanna is the Drug Metabolism and Disposition Highlighted Trainee Author for the November 2023 issue. She is currently a fifth-year PhD candidate at the College of Pharmacy and Pharmaceutical Sciences, Washington State University, working under the mentorship of Dr. John Clarke. The DMD article that earned her selection as a Highlighted Trainee Award is titled: "Goldenseal-Mediated Inhibition of Intestinal Uptake Transporters Decreases Metformin Systemic Exposure in Mice" and is available here: https://doi.org/10.1124/dmd.123.001360.
Ms. Oyanna’s research investigates the solubility and transporter mechanisms underlying pharmacokinetic botanical natural product-drug interactions. Her work encompasses various botanical natural products, including goldenseal, green tea, kratom, and silymarin. She is currently examining the role of solubility in pharmacokinetic green tea-drug interactions. Her work addresses a critical area of concern, delving into natural products’ modulation of drug solubility.
The anticipated impact of Ms. Oyanna’s work is to reduce and prevent undesirable clinical outcomes such as reduced drug efficacy and adverse drug effects by enhancing our understanding of different mechanisms governing intestinal natural product-drug interactions.
Outside her research, Victoria enjoys podcasts and volunteering. She also enjoys exploring new experiences.