Studies in recent decades have provided convincing evidence that many ATP-binding cassette (ABC) and solute carrier (SLC) transporters play pivotal roles in the absorption, distribution, metabolism and elimination of drugs and xenobiotics. The special section of the May 2018 issue of Drug Metabolism and Disposition contains over 20 original manuscripts, perspectives and reviews that highlight the most recent advances in several of the transporter research areas, including basic biology and function of transporters, expression of drug transporters in organ and tissue barriers, the mechanisms underlying regulation of transporter expression, transporter-mediated drug disposition in animal models, and the development and utilization of new technologies in drug transporter study as well as pharmacokinetic modeling and simulation to assess transporter involvement in drug disposition and drug-drug interactions.

See the special section at Drug Metabolism and Disposition May 2018. These articles are freely accessible through July 15.