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ASPET Presidential Symposium: Deadly Liaisons: Squeezing the Life Out of Cancer

Sunday April 22, 2018

9:30 am - 12:00 pm

Room 16A
Co-sponsored by the Division for Cancer Pharmacology (DCP)

Chair :

John Schuetz
St. Jude Children's Research Hospital

Mary-Ann Bjornsti
University of Alabama-Birmingham

Recent scientific advances have brought significant progress in cancer treatment, but also reveal the challenges and complexities of pharmacologically targeting cancer. These advances extend from genomics, to chemical biology, to acquiring knowledge of the unique susceptibilities of individual cancers that drive drug discovery. This symposium provides a state-of-the art overview of Cancer Pharmacology by international leaders in their respective fields. Topics include: using genomics to elucidate the determinants of anticancer drug toxicity and efficacy; discovering druggable pathways in novel, clinically relevant models of the most deadly CNS pediatric cancers; how deciphering the mechanism of action of a natural product, taxol, catalyzed breakthroughs in cancer therapy; and discovering small molecules that disrupt protein interactions, which cancers depend upon.

Precision Medicine of Childhood Acute Lymphoblastic Leukemia: From Discovery to Translation
William Evans - St. Jude Children's Research Hospital

Taxol®, Tubulin and Tumors: A Story of Drug Development
Susan Band Horwitz - Albert Einstein College of Medicine

Identification of New Therapies to Treat Pediatric Medulloblastoma
Martine Roussel - St. Jude Children's Research Hospital

Discovery of Inhibitors of the Interaction of UBC12 and DCN1
R. Kiplin Guy - University of Kentucky School of Pharmacy

Thank you to our Annual Meeting partners:

University of Florida
Wake Forest University
Washington State University College of Pharmacy and Pharmaceutical Sciences
University of Wisconsin Molecular and Cellular Pharmacology Training Program
UT Health San Antonio
University of Minnesota

Emory University Pharmacology

PR & P
University of Michigan Medical School Pharmacology