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Division for Drug Metabolism and Disposition Gillette Awards and Junior Investigator Platform Session

Tuesday April 24, 2018

3:30 pm - 6:00 pm Eastern Time (ET)

Room 16B


Chair :

Xinxin Ding
University of Arizona College of Pharmacy

Nina Isoherranen
University of Washington

This session showcases abstract-based oral presentations by graduate student and postdoctoral ASPET members focused on drug metabolism and disposition. It also features the best papers from the Drug Metabolism and Disposition journal whose authors will receive the James R. Gillette Award and give short talks about their work.


Jiong Yan - University of Pittsburgh

Cell-Specific Role of Aryl Hydrocarbon Receptor in Liver Fibrosis

Ana Vergara - Washington State University

Detoxification of Polycyclic Aromatic Hydrocarbons (PAHs) by UDP-glycosyltransferase 3A2 (UGT3A2) Variants using Alternative Sugars

Kodye Abbott - Auburn University

Belinostat Inhibits Rifampicin Induced CYP3A4 and MDR1 Gene Expression

Bing Qi - KU Leuven

In Vitro Evaluation of the Hepatic Disposition of Colistin

Patrick Garcia - University of Alabama-Birmingham

Utilizing SULT4A1 Mutant Mouse Models to Characterize SULT4A1

Ajay Donepudi - University of Connecticut

Multidrug Resistance Protein 4 (Mrp4), A Drug Transporter is a Novel Genetic Determinant for Adipogenesis

Guo Zhong - University of Washington

Differential Inactivation Mechanism and Covalent Adduct Formation of ALDH1A1 and ALDH1A2 by WIN18,446

Casey Dorr - Minneapolis Medical Research Foundation at Hennepin County Medical Center

CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism

Marilyn Giacomini - Gilead Sciences

Interaction of 2,4-Diaminopyrimidine Containing Drugs Including Fedratinib and Trimethoprim with Thiamine Transporters