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Division for Drug Metabolism and Disposition Gillette Awards and Junior Investigator Platform Session

Tuesday April 24, 2018

3:30 pm - 6:00 pm

Room 16B
Sponsored by the Division for Drug Metabolism and Disposition (DMDD)

Chair :

Xinxin Ding
University of Arizona College of Pharmacy

Nina Isoherranen
University of Washington

This session showcases abstract-based oral presentations by graduate student and postdoctoral ASPET members focused on drug metabolism and disposition. It also features the best papers from the Drug Metabolism and Disposition journal whose authors will receive the James R. Gillette Award and give short talks about their work.

Cell-Specific Role of Aryl Hydrocarbon Receptor in Liver Fibrosis
Jiong Yan - University of Pittsburgh

Detoxification of Polycyclic Aromatic Hydrocarbons (PAHs) by UDP-glycosyltransferase 3A2 (UGT3A2) Variants using Alternative Sugars
Ana Vergara - Washington State University

Belinostat Inhibits Rifampicin Induced CYP3A4 and MDR1 Gene Expression
Kodye Abbott - Auburn University

In Vitro Evaluation of the Hepatic Disposition of Colistin
Bing Qi - KU Leuven

Utilizing SULT4A1 Mutant Mouse Models to Characterize SULT4A1
Patrick Garcia - University of Alabama-Birmingham

Multidrug Resistance Protein 4 (Mrp4), A Drug Transporter is a Novel Genetic Determinant for Adipogenesis
Ajay Donepudi - University of Connecticut

Differential Inactivation Mechanism and Covalent Adduct Formation of ALDH1A1 and ALDH1A2 by WIN18,446
Guo Zhong - University of Washington

CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism
Casey Dorr - Minneapolis Medical Research Foundation at Hennepin County Medical Center

Interaction of 2,4-Diaminopyrimidine Containing Drugs Including Fedratinib and Trimethoprim with Thiamine Transporters
Marilyn Giacomini - Gilead Sciences

Thank you to our Annual Meeting partners:

University of Florida
Wake Forest University
Washington State University College of Pharmacy and Pharmaceutical Sciences
University of Wisconsin Molecular and Cellular Pharmacology Training Program
UT Health San Antonio
University of Minnesota

Emory University Pharmacology

PR & P
University of Michigan Medical School Pharmacology