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There’s Always Room for Dessert: Examining the Effect of Insulin and High Fat Diet on Neurotransmission, Motivation and Cognition

Tuesday April 24, 2018

9:30 am - 12:00 pm

Room 17A
Sponsored by the Division for Neuropharmacology (NEU)
Co-sponsored by the Division for Behavioral Pharmacology (BEH)
Co-sponsored by the Division for Cardiovascular Pharmacology (CVP)

Chair :

Carrie Ferrario
University of Michigan

Lawrence Reagan
University of South Carolina School of Medicine


Recent studies have revealed roles for insulin beyond homeostatic regulation. For example, insulin influences glutamatergic and dopaminergic transmission in the central nervous system, suggesting roles for insulin in the regulation of motivation, and the potential to target brain insulin receptors to improve cognition and motivational control. Speakers will provide a well-rounded view of current data describing the mechanisms by which insulin influences neurotransmisson and behavior, and how diet modulates brain function. Presentations will draw on multiple levels of analysis (behavior, voltammetry, electrophysiology), integrate research from several broad fields, and discuss implications for treatment of cognitive impairment, obesity and addiction.

How Sweet It Is: Diet, Insulin, Dopamine, and Reward
Margaret Rice - New York University School of Medicine

Fighting Fat with Fat: Dietary Supplementation with Omega-3 Fatty Acids Prevents and Reverses High Fat Diet-Induced Enhanced Sensitivity to the Behavioral Effects of Dopaminergic Drugs
Katherine Serafine - University of Texas at El Paso

Why Did I Eat That? Effects of Insulin on Striatal Glutamatergic Transmission and Food-Seeking
Carrie Ferrario - University of Michigan

Do You Remember What You Had for Lunch? Novel Roles for Insulin in Cognition and Hippocampal Plasticity
Lawrence Reagan - University of South Carolina School of Medicine

Effects of Chronic, Intermittent Sucrose Consumption on the Discriminative Stimulus Effects of Dopamine or Opioid Antagonists
Morgan Marek - University of Wisconsin-Eau Claire

Thank you to our Annual Meeting partners:

Amgen
University of Florida
Wake Forest University
Washington State University College of Pharmacy and Pharmaceutical Sciences
University of Wisconsin Molecular and Cellular Pharmacology Training Program
UT Health San Antonio
University of Minnesota

Emory University Pharmacology

PR & P
University of Michigan Medical School Pharmacology
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