In This Section

RNA Binding Proteins in Cardiovascular Disease

Monday April 23, 2018

9:30 am - 12:00 pm Eastern Time (ET)

Room 15A

CVP

Chair :

Michael Tranter
University of Cincinnati

Elizabeth Tarling
University of California, Los Angeles



RNA binding proteins as key post-transcriptional mediators of gene expression in multiple cardiovascular disease processes. There are over 1000 RNA binding proteins expressed in human cells, and a large percentage of these proteins have been implicated in the development of one or more diseases. This diverse class of proteins play central roles in cardiac development as well steady-state and pathophysiological processes by regulating mRNA splicing, transport, stability and translation. This symposium will focus on the role of RNA binding proteins in the regulation of cardiovascular diseases.

Speakers

Hossein Ardehali - Northwestern University

The Role of Tristetraprolin (TTP) in Regulating Cardiac Iron Homeostasis and Metabolism

Michael Tranter - University of Cincinnati

Cardiac-specific Deletion of the RNA Binding Protein HuR Protects Against Pathological Cardiac Hypertrophy

Muge Kuyumcu-Martinez - University of Texas - Medical Branch

The Role of RNA Binding Protein rbfox2 in Human Heart Diseases

Prasanna Krishnamurthy - University of Alabama-Birmingham

HuR: Novel Regulator of Cardiovascular Pathophysiology

Carlos Fernandez-Hernando - Yale University

Post-transcriptional Regulation of Cholesterol Homeostasis as a Mediator of Atheroslcerosis

Lauren Haar - Loyola University Chicago

The Addition of GFP to Exosomes Influences Cardioprotective Potential Through an RNA Binding Mechanism

Elizabeth Tarling - University of California, Los Angeles

ZFP36L1 is a Post-transcriptional Regulator of Lipid Metabolism