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An Apel(-in) a Day Keeps Cardiovascular Disorders at Bay?

Saturday April 06, 2019

11:00 am - 1:00 pm

Room W206 A
Co-sponsored by the Division for Cardiovascular Pharmacology (CVP)
Co-sponsored by the Division for Drug Discovery and Development (DDD)
Co-sponsored by the Division for Molecular Pharmacology (MP)

Chair :

Hyung Chun
Yale University

Rangan Maitra
RTI International

The apelin receptor system has recently emerged as an exciting new drug target. Come learn about the fascinating journey of this GPCR from the bench to the bedside at this symposium. The apelin receptor is an important player in various types of cardiovascular diseases including heart failure, metabolic syndrome and preeclampsia. Major pharmaceutical companies have recently initiated clinical trials targeting this receptor system. An international panel of experts will present cutting-edge research from their laboratories with an eye on drug development using peptides and small molecules.

Cardiometabolic Role of APJ
Hyung Chun - Yale University

The Elabela-Ergic Pathway: From Pluripotency to Preeclampsia
Bruno Reversade - Institute of Molecular and Cellular Biology, A*STAR, Singapore

Biased APJ Ligands for Heart Failure
Rangan Maitra - RTI International

The Apelinergic System in Type 2 Diabetes: From Bench to Bedside
Isabelle Castan-Laurell - INSERM U1048 I2MC

Hemodynamic Effects of Apelin in Preeclampsia
Liliya Yamaleyeva - Wake Forest University School of Medicine

Using CRISPR/Cas9 and NanoLuc to Investigate ‘Endogenous’ CXCR4 Ligand Binding, Internalisation and β-arrestin2 Recruitment
Carl White - University of Nottingham

Last Updated: August 15, 2019
Key Dates
April 6

ASPET Business Meeting and Awards Presentation

April 6-9

ASPET Annual Meeting at EB 2019

Thank you to our Annual Meeting partners:

University of Florida
Wake Forest University
Washington State University College of Pharmacy and Pharmaceutical Sciences
University of Wisconsin Molecular and Cellular Pharmacology Training Program
UT Health San Antonio
University of Minnesota

Emory University Pharmacology

PR & P
University of Michigan Medical School Pharmacology