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Axelrod Symposium: Phosphoproteomic Analysis of G Protein-Coupled Pathways

Sunday April 07, 2019

3:00 pm - 5:00 pm Eastern Time (ET)

Room W205 BC


Chair :

Joe Beavo
University of Washington

Mark von Zastrow
University of California, San Francisco

This symposium will address some of the newer methods of unbiased, phosphoproteomic approaches to the analysis of physiological and pharmacological regulation of G-protein coupled receptor pathways. Several different G-protein coupled pathways will be discussed and compared. Data will be presented about how specific compartmentalization of pathways can be dissected using changes in phosphoproteomic profiles in the presence and absence of pathway selective drugs. There will also be a discussion of how phosphoproteomic analyses can be used in conjunction with cellular imaging techniques to analyze compartmentalized signaling.

Supported by the John V. Croker Fund


Mark Knepper - National Heart, Lung, and Blood Institute

Phosphoproteomic Identification of Vasopressin V2 Receptor-Dependent Signaling

Kjetil Taskén - Oslo University Hospital

High-resolution Mapping and Systems Analysis of the Prostanoid E Receptor 1-4 (EP1-4) Signaling Network in T Cell Subsets by Quantitative Phosphoproteomics and Phosphoflow Cytometry

Manuela Zaccolo - University of Oxford

Defining a Cellular map of cAMP Nanodomains Using Real-time Imaging and Mass Spectrometry

Mark von Zastrow - University of California, San Francisco

Proteomic Approaches GPCR Signaling and Regulation

Last Updated: August 15, 2019
Key Dates
April 6

ASPET Business Meeting and Awards Presentation

April 6-9

ASPET Annual Meeting at EB 2019