In This Section

Cardiovascular Signaling via the G Protein-Coupled Estrogen Receptor

Tuesday April 09, 2019

8:00 am - 10:00 am

Room W205 BC
Sponsored by the Division for Cardiovascular Pharmacology (CVP)
Co-sponsored by the Division for Molecular Pharmacology (MP)

Chair :

Sarah Lindsey
Tulane University

Kim Tran
Des Moines University

The predominant female sex hormone estrogen impacts virtually all aspects of cardiovascular health. Estrogen receptors alpha and beta are classical estrogen receptors that have been extensively studied over the past several decades. The G protein-coupled estrogen receptor 1 (GPER, aka GPR30) was more recently identified and has since been implicated in numerous cardiovascular processes. This symposium will feature recent developments in GPER signaling mechanisms in the cardiovascular system, including novel findings, challenges, therapeutic applicability, and knowledge gaps. The presentations will incorporate paradigms in pharmacology, biochemistry, physiology, and pathophysiology with techniques spanning from the molecular to whole animal level.

GPER Signaling in Vascular Disease
Sarah Lindsey - Tulane University

GPER: A Moderator of Cardiovascular Signaling
Kim Tran - Des Moines University

Estrogen Receptor-α Counterbalances the Endotoxic Inflammatory Response and Associated Arterial Baroreflex Dysfunction in Ovariectomized Rats
Mohammed El-Lakany - Alexandria University

Aldosterone Binding to G Protein Estrogen Receptor - GPER
Qingming Ding - St. Boniface Hospital Albrectsen Research Centre

Female Heart Health: Is GPER the Missing Link?
Leanne Groban - Wake Forest University

The Yin Yang of GPER Regulation in Cardiovascular Function
Eric Prossnitz - University of New Mexico

Last Updated: August 15, 2019
Key Dates
April 6

ASPET Business Meeting and Awards Presentation

April 6-9

ASPET Annual Meeting at EB 2019

Thank you to our Annual Meeting partners:

University of Florida
Wake Forest University
Washington State University College of Pharmacy and Pharmaceutical Sciences
University of Wisconsin Molecular and Cellular Pharmacology Training Program
UT Health San Antonio
University of Minnesota

Emory University Pharmacology

PR & P
University of Michigan Medical School Pharmacology