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New Opportunities in Targeting WNT Signaling

Monday April 08, 2019

2:00 pm - 3:30 pm

Room W205 A
Sponsored by the Division for Molecular Pharmacology (MP)
Co-sponsored by the Division for Cardiovascular Pharmacology (CVP)
Co-sponsored by the Division for Drug Discovery and Development (DDD)

Chair :

Gunnar Schulte
Karolinska Institutet

W. Matthijs Blankesteijn
CARIM, Maastricht University, The Netherlands

The role of WNT signaling in pathological conditions such as cancer, cardiovascular disease and neurodegeneration is now well established and there is increasing interest in therapeutic exploitation of the pathway. In this symposium we will focus on new developments in WNT signaling activation and the rapidly developing opportunities for targeting the pathway at multiple levels in a context of cancer and cardiovascular disease. Next, the translational perspective will be discussed, followed by three short presentations by junior researchers, selected from the abstracts. The symposium will be concluded by a panel discussion where input from the audience will be addressed.

Deeper Insight into FZD Activation Mechanisms Provides a New Link to Cancer
Gunnar Schulte - Karolinska Institutet

Mudulation of Stem Cell Activity by WNT Signaling in Cancer Therapy
David Virshup - Duke-NUS Medical School

Interventions in WNT Signaling Stimulate Cardiac Regeneration
W. Matthijs Blankesteijn - CARIM, Maastricht University, The Netherlands

Panel Discussion

Last Updated: August 15, 2019
Key Dates
April 6

ASPET Business Meeting and Awards Presentation

April 6-9

ASPET Annual Meeting at EB 2019

Thank you to our Annual Meeting partners:

University of Florida
Wake Forest University
Washington State University College of Pharmacy and Pharmaceutical Sciences
University of Wisconsin Molecular and Cellular Pharmacology Training Program
UT Health San Antonio
University of Minnesota

Emory University Pharmacology

PR & P
University of Michigan Medical School Pharmacology