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New Paradigms for Targeting Adenosine Receptors: Basic and Translational Applications

Tuesday April 09, 2019

2:00 pm - 3:30 pm

Room W206 A
Sponsored by the Division for Translational and Clinical Pharmacology (TCP)
Co-sponsored by the Division for Behavioral Pharmacology (BEH)
Co-sponsored by the Division for Cardiovascular Pharmacology (CVP)
Co-sponsored by the Division for Molecular Pharmacology (MP)

Chair :

Ross Corriden
Merck

Lauren May
Monash Institute of Pharmaceutical Sciences, Monash University


Adenosine is one of the body’s most vital cytoprotective molecules, mediating its effects through the adenosine family of G protein-coupled receptors. This receptor family has an essential role in physiology and pathophysiology, particularly in response to stress and injury, and therefore represents potential targets for the treatment of major global health burdens such as ischaemia-reperfusion injury, neuropathic pain and inflammation. This symposium will highlight recent advances in the mechanistic understanding and therapeutic exploitation of adenosine receptors across a variety of disease states, providing novel approaches for overcoming the preclinical-clinical bottleneck in targeting this vital receptor family.

Translational Successes and Failures of Adenosine Receptor Therapeutics
Kenneth Jacobson - National Institute of Diabetes and Digestive and Kidney Disease, NIH

Drug-Target Binding Kinetics – A Case for Adenosine Receptors
Laura Heitman - LACDR, Leiden University

Adenosine Receptor Context-Specific Biased Agonism to Treat Ischemic Heart Disease
Lauren May - Monash Institute of Pharmaceutical Sciences, Monash University

Targeting Adenosine Receptors to Regulate Immune Responses
Joel Linden - La Jolla Institute for Allergy and Immunology

Last Updated: August 15, 2019
Key Dates
April 6

ASPET Business Meeting and Awards Presentation

April 6-9

ASPET Annual Meeting at EB 2019

Thank you to our Annual Meeting partners:

Amgen
University of Florida
Wake Forest University
Washington State University College of Pharmacy and Pharmaceutical Sciences
University of Wisconsin Molecular and Cellular Pharmacology Training Program
UT Health San Antonio
University of Minnesota

Emory University Pharmacology

PR & P
University of Michigan Medical School Pharmacology
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