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Targeting Adipose Inflammation in Diabetic Vascular Complications

Monday April 08, 2019

8:00 am - 10:00 am

Room W206 A
Sponsored by the Division for Cardiovascular Pharmacology (CVP)
Co-sponsored by the Division for Drug Discovery and Development (DDD)

Chair :

Rhian Touyz
University of Glasgow

Ahmed El-Yazbi
The American University of Beirut

Vasculoprotective pleiotropic effects of anti-diabetic drugs have received a lot of attention since the emergence of recent clinical data describing significant cardiovascular risk reduction in diabetic and/or prediabetic patients treated with certain molecules independent of their hypoglycemic effect. This symposium explores the detrimental role that adipose tissue inflammation plays in the development cardiovascular complications of diabetes. Recent findings regarding signaling pathways underling this deleterious interaction will be presented. Several potential therapeutic targets will be explored, together with novel therapeutic tools currently under clinical investigation. As well, new protective mechanisms for traditional drugs via modulation of adipose inflammation will be highlighted.

Adipose Inflammation in Pre-diabetes and Insulin Resistance
Michael Czech - University of Massachusetts Medical School

Detrimental Signaling from Dysfunctional Adipose Tissue to Vasculature
Rhian Touyz - University of Glasgow

Metabolic Disease and Adipose Tissue Senescence: Potential Interventions in Diabetes
Allyson Palmer - Mayo Clinic College of Medicine and Science

Adipose Tissue Inflammation and Vascular Dysfunction Preceding Hyperglycemia: Modulation by Anti-Diabetic Drugs
Ahmed El-Yazbi - The American University of Beirut

Therapeutic Targets in Adipose Tissue in Obesity Related Heart Failure with Preserved Ejection Fraction
Gavin Oudit - University of Alberta

Last Updated: August 15, 2019
Key Dates
April 6

ASPET Business Meeting and Awards Presentation

April 6-9

ASPET Annual Meeting at EB 2019

Thank you to our Annual Meeting partners:

University of Florida
Wake Forest University
Washington State University College of Pharmacy and Pharmaceutical Sciences
University of Wisconsin Molecular and Cellular Pharmacology Training Program
UT Health San Antonio
University of Minnesota

Emory University Pharmacology

PR & P
University of Michigan Medical School Pharmacology