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Team Science: From Molecules to Test Tubes to Behavior

Tuesday April 09, 2019

4:00 pm - 6:00 pm

Room W205 BC
Sponsored by the Division for Behavioral Pharmacology (BEH)
Co-sponsored by the Division for Drug Discovery and Development (DDD)
Co-sponsored by the Division for Neuropharmacology (NEU)

Chair :

Gregory Collins
University of Texas Health Science Center at San Antonio

James Cook
University of Wisconsin Milwaukee


The symposium will highlight two teams of researchers, focusing on how highly collaborative interactions between medicinal chemists and behavioral pharmacologists facilitate the development and investigation of novel therapeutics. Each team will describe findings ranging from chemical design and synthesis to in vivo evaluation, with one team focused on positive allosteric modulators of α2/3 containing GABA A receptors, and the other focused on mitragynine and related analogs as a novel class of mu-opioid receptor agonists. These teams will demonstrate how scientists from these different fields communicate and educate each other, emphasizing the challenges and successes of these important scientific relationships.

Improved Antiepileptic Profile with α2/3-selective GABAA Receptor PAMs
James Cook - University of Wisconsin Milwaukee

Anxiolytic and Abuse-related Effects of Novel α2/3-selective GABAA Receptor PAMs
Lais Berro - University of Mississippi Medical Center

A Novel Non-Opiate Treatment for Chronic Pain
Jun-Xu Li - University of Buffalo

Mitragyna Speciosa: Phytochemistry in Plants and Biotransformation in Animals
Christopher McCurdy - University of Florida

Pharmacological Mechanisms of Mitragyna Speciosa Alkaloids
Lance McMahon - University of Florida

Last Updated: August 15, 2019
Key Dates
April 6

ASPET Business Meeting and Awards Presentation

April 6-9

ASPET Annual Meeting at EB 2019

Thank you to our Annual Meeting partners:

Amgen
University of Florida
Wake Forest University
Washington State University College of Pharmacy and Pharmaceutical Sciences
University of Wisconsin Molecular and Cellular Pharmacology Training Program
UT Health San Antonio
University of Minnesota

Emory University Pharmacology

PR & P
University of Michigan Medical School Pharmacology
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