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Team Science: From Molecules to Test Tubes to Behavior

Tuesday April 09, 2019

4:00 pm - 6:00 pm Eastern Time (ET)

Room W205 BC


Chair :

Gregory Collins
University of Texas Health Science Center at San Antonio

James Cook
University of Wisconsin Milwaukee

The symposium will highlight two teams of researchers, focusing on how highly collaborative interactions between medicinal chemists and behavioral pharmacologists facilitate the development and investigation of novel therapeutics. Each team will describe findings ranging from chemical design and synthesis to in vivo evaluation, with one team focused on positive allosteric modulators of α2/3 containing GABA A receptors, and the other focused on mitragynine and related analogs as a novel class of mu-opioid receptor agonists. These teams will demonstrate how scientists from these different fields communicate and educate each other, emphasizing the challenges and successes of these important scientific relationships.


James Cook - University of Wisconsin Milwaukee

Improved Antiepileptic Profile with α2/3-selective GABAA Receptor PAMs

Lais Berro - University of Mississippi Medical Center

Anxiolytic and Abuse-related Effects of Novel α2/3-selective GABAA Receptor PAMs

Jun-Xu Li - University of Buffalo

A Novel Non-Opiate Treatment for Chronic Pain

Christopher McCurdy - University of Florida

Mitragyna Speciosa: Phytochemistry in Plants and Biotransformation in Animals

Lance McMahon - University of Florida

Pharmacological Mechanisms of Mitragyna Speciosa Alkaloids

Last Updated: August 15, 2019
Key Dates
April 6

ASPET Business Meeting and Awards Presentation

April 6-9

ASPET Annual Meeting at EB 2019