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GPCR Colloquium

Joint Colloquium on G Protein-Coupled Receptors: Evolving Insights from Pharmacology, Biochemistry and Physiology

Hosted by ASPET, ASBMB, and APS

Monday, May 10 – Tuesday, May 11, 2021

Tremendous scientific advancements over the last decade indicate that GPCR physiology and pharmacology are much more complex than originally thought and that it may be possible to exploit this complexity to treat a wide variety of diseases. The objective of this colloquium is to expose scientists to recent discoveries and multidisciplinary approaches used to study GPCRs and provide opportunities for establishing collaborations that bridge complementary interests. The event will feature speakers who have made exciting discoveries in GPCR research that range from molecular to systems biology, basic research to translational studies, and pharmacology to biochemistry to physiology.

Co-Chairs

Tracy M. Handel – University of California, San Diego
Paul Insel – University of California, San Diego
Jennifer Pluznick - Johns Hopkins University School of Medicine

Preliminary Program

Keynote

Brian Kobilka - Stanford University
Structural Insights into the Dynamic Process of G Protein–Coupled Receptor Activation

Symposia

Systems Biology Approaches to GPCR Physiology and Pharmacology

Mark Knepper – NHLBI
V2R-omics: Multi-systems Approaches to Define Vasopressin Action

Nina Wettschureck – Max Planck Institute for Heart and Lung Research
Single Cell Analysis of GPCR Expression: Implication for Physiology and Pathophysiology

Kirill Martemyanov - The Scripps Research Institute
Deciphering Diversity of GPCR Signaling

Sriram Kosuri - Univ. of California, Los Angeles
Combining Synthesis and Multiplexed Assays to Explore Human Biology: GPCRs as a Paradigm

GPCR Structural Biology and Drug Discovery

Chris Tate – Cambridge Univ.
Molecular Basis for High-affinity Agonist Binding at the Beta1-adrenoceptor

Bryan Roth – Univ. of North Carolina
New Technologies for Structure-guided GPCR Drug Discovery

Minghong Ma – Univ. of Pennsylvania
G Protein–Coupled Olfactory Receptors: Novel Insights into Responsiveness and Mechano-Sensitivity

Laura Wingler – Duke Univ.
Molecular Mechanisms of Biased Signaling at the Angiotensin Receptor

GPCRs in Pathophysiology and Pathobiology

Jerold Chun - Sanford Burnham Prebys.
SIP, LPA and Their Receptors in CNS Disorders

Kathleen Caron – Univ. of North Carolina
Novel Regulatory Functions of GPCRs in Vascular Growth and Remodeling

Willis (Rick) Samson – St. Louis Univ.
Novel Peptide-activated (Orphan) GPCRs: New Insights and Therapeutic Opportunities

Lora Heisler – Univ. of Aberdeen
Targeting GPCRs to Improve Obesity

Virtual Posters

Virtual posters at the Colloquium will include a PDF poster with a 5-minute audio narration by the author as well as a text-based Q&A discussion board.

All abstracts submitted during the regular submission period to the topic category “3016-ASPET GPCR Colloquium” will be reviewed and considered for inclusion at the Colloquium. Accepted abstracts will be programmed at both the main EB meeting and the GPCR Colloquium.

Abstracts can also be submitted from January 14 to February 4, 2021 during the Last-Chance abstract submission period to any ASPET topic category. Please use GPCR as one of your keywords.

If you already submitted or plan to submit to another topic category or society, please email meetings@aspet.org with your abstract ID number and we can be sure you are considered for both the Colloquium and EB. Please do not submit duplicate abstracts.

Submit Abstract

Registration

Thanks to the generosity of our sponsors and support from ASPET, ASBMB, and APS, a ticket for the colloquium is being provided at no extra charge with your paid registration to Experimental Biology.

Register Now