Pooja Hegde, PhD, is the Drug Metabolism and Disposition Highlighted Trainee Author for March 2025. Pooja is a Drug Metabolism-Pharmacokinetics (DMPK) Advisor.

The MolPharm article that earned her the selection as highlighted Trainee Author is titled “Improvement in static and dynamic projections of drug-drug interactions caused by cytochrome P4503A time-dependent inhibitors through in vitro allosteric modulation by progesterone” and is available at: https://doi.org/10.1016/j.dmd.2024.10003.

When asked how she hopes her work will impact the field of pharmacology, she says, “While the preclinical DMPK field is constantly developing, there are still a few challenges with regards to drug metabolizing enzymes and drug-drug interactions (DDIs). I hope my research will help address a few gaps in the field and will improve the in-vitro to in-vivo correlation abilities to have a better understanding of risk prediction and to enhance screening of compounds for DDIs early in the discovery stage.”